METAP2 anticorps (AA 201-474) (HRP)

N° du produit ABIN8009502

L’anticorps anti-METAP2 Polyclonal Lapin est utilisé pour la détection de METAP2 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour METAP2 anticorps (AA 201-474) (HRP) (ABIN8009502)

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METAP2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-METAP2 anticorps (HRP)

Épitope: AA 201-474

Fonction: Anti-METAP2 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human METAP2 recombinant protein (Position: E201-R474).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: METAP2

Sujet:

Background: Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: methionyl aminopeptidase 2

ID gène: 10988

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling