GANP anticorps (AA 1275-1715) (Cy3)

N° du produit ABIN8010334

Cet anticorps anti-GANP Polyclonal Lapin conjugué à Cy3 (ABIN8010334) détecte spécifiquement GANP dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GANP anticorps (AA 1275-1715) (Cy3) (ABIN8010334)

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GANP est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-GANP anticorps (Cy3)

Épitope: AA 1275-1715

Fonction: Anti-GANP/MCM3AP Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human MCM3AP shares 80.9% amino acid (aa) sequence identity with mouse MCM3AP.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GANP/MCM3AP recombinant protein (Position: R1275-H1715). Human MCM3AP shares 80.9% amino acid (aa) sequence identity with mouse MCM3AP.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GANP

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Autre désignation: MCM3AP

Sujet:

Background: 80 kDa MCM3-associated protein is a protein that in humans is encoded by the MCM3AP gene. The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.

Gene Full Name: minichromosome maintenance complex component 3 associated protein

ID gène: 8888

UniProt: O60318

Pathways: Protein targeting to Nucleus