MYBL1 anticorps (AA 199-752) (Cy3)

N° du produit ABIN8012259

L’anticorps anti-MYBL1 Polyclonal Lapin est utilisé pour la détection de MYBL1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour MYBL1 anticorps (AA 199-752) (Cy3) (ABIN8012259)

Antigène: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYBL1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MYBL1 anticorps (Cy3)

Épitope: AA 199-752

Fonction: Anti-v-Myb/MYBL1 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human v-Myb/MYBL1 recombinant protein (Position: K199-L752).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MYBL1

Antigène: MYBL1 (Myb-Like Protein 1 (MYBL1))

Autre désignation: MYBL1

Sujet:

Background: MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t (14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

Gene Full Name: MYB proto-oncogene like 1

ID gène: 4603

UniProt: P10243

Pathways: Cycle Cellulaire, Chromatin Binding