MYLK anticorps (AA 1441-1709) (Cy3)

N° du produit ABIN8012755

Cet anticorps anti-MYLK Polyclonal Lapin conjugué à Cy3 (ABIN8012755) détecte spécifiquement MYLK dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MYLK anticorps (AA 1441-1709) (Cy3) (ABIN8012755)

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MYLK anticorps (Cy3)

Épitope: AA 1441-1709

Fonction: Anti-Myosin light chain kinase/MYLK Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human MYLK recombinant protein (Position: D1441-D1709).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MYLK

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Autre désignation: MYLK

Sujet:

Background: Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene. This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin.

Gene Full Name: myosin light chain kinase

ID gène: 4638

UniProt: Q15746