NDFIP2 anticorps (AA 16-336) (Fluoro550)

N° du produit ABIN8014144

Cet anticorps anti-NDFIP2 Polyclonal Lapin conjugué à Fluoro550 (ABIN8014144) détecte spécifiquement NDFIP2 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NDFIP2 anticorps (AA 16-336) (Fluoro550) (ABIN8014144)

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDFIP2 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-NDFIP2 anticorps (Fluoro550)

Épitope: AA 16-336

Fonction: Anti-NDFIP2 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NDFIP2

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Autre désignation: NDFIP2

Sujet:

Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Gene Full Name: Nedd4 family interacting protein 2

ID gène: 54602

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome