NGFR anticorps (AA 29-240) (Fluoro550)

N° du produit ABIN8014342

Cet anticorps anti-NGFR Polyclonal Lapin conjugué à Fluoro550 (ABIN8014342) détecte spécifiquement NGFR dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour NGFR anticorps (AA 29-240) (Fluoro550) (ABIN8014342)

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NGFR est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-NGFR anticorps (Fluoro550)

Épitope: AA 29-240

Fonction: Anti-p75 NGF Receptor/NGFR Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human p75 NGF Receptor/NGFR recombinant protein (Position: K29-Q240).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NGFR

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Autre désignation: NGFR

Sujet:

Background: The low-affinity nerve growth factor receptor (nerve growth factor receptor (TNFR superfamily, member 16), also called the LNGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins, a family of protein growth factors that stimulate neuronal cells to survive and differentiate. LNGFR is a member of the tumor necrosis factor receptor (TNF receptor)superfamily indeed, LNGFR was the first member of this large family of receptors to be characterized. It is mapped to 17q21.33. Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

Gene Full Name: nerve growth factor receptor

ID gène: 4804

UniProt: P08138

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding