NFKBIB anticorps (AA 96-356) (HRP)
Aperçu rapide pour NFKBIB anticorps (AA 96-356) (HRP) (ABIN8015313)
Antigène
Voir toutes NFKBIB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 96-356
-
Fonction
- Anti-IkB Beta/NFKBIB Antibody HRP Conjugated
-
Homologie
- Human NFKBIB shares 79.5%,76.4% amino acid (aa) sequence identity with mouse,rat NFKBIB,respectively.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human IkB Beta/NFKBIB recombinant protein (Position: T96-V356). Human NFKBIB shares 79.5% and 76.4% amino acid (aa) sequence identity with mouse and rat NFKBIB, respectively.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
Stock
- -20 °C
-
Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
-
Autre désignation
- NFKBIB
-
Sujet
-
Background: NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: NFKB inhibitor beta
-
ID gène
- 4793
-
UniProt
- Q15653
-
Pathways
- Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
Antigène
-