NK2 Homeobox 5 anticorps (Middle Region) (Fluoro488)

N° du produit ABIN8015771

Cet anticorps Lapin Polyclonal détecte spécifiquement NK2 Homeobox 5 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour NK2 Homeobox 5 anticorps (Middle Region) (Fluoro488) (ABIN8015771)

Antigène: NK2 Homeobox 5 (NKX2-5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NK2 Homeobox 5 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-NK2 Homeobox 5 anticorps (Fluoro488)

Épitope: Middle Region

Fonction: Anti-Nkx2.5/NKX2-5 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Nkx2.5, different from the related mouse and rat sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NK2 Homeobox 5

Antigène: NK2 Homeobox 5 (NKX2-5)

Autre désignation: NKX2-5

Sujet:

Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

Gene Full Name: NK2 homeobox 5

Sequence Similarities: Belongs to the NK-2 homeobox family.

ID gène: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development