NK2 Homeobox 5 anticorps (AA 15-132) (APC)

N° du produit ABIN8015787

L’anticorps anti-NK2 Homeobox 5 Polyclonal Lapin est utilisé pour la détection de NK2 Homeobox 5 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour NK2 Homeobox 5 anticorps (AA 15-132) (APC) (ABIN8015787)

Antigène: NK2 Homeobox 5 (NKX2-5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NK2 Homeobox 5 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-NK2 Homeobox 5 anticorps (APC)

Épitope: AA 15-132

Fonction: Anti-Nkx2.5/NKX2-5 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Nkx2.5/NKX2-5 recombinant protein (Position: K15-R132).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NK2 Homeobox 5

Antigène: NK2 Homeobox 5 (NKX2-5)

Autre désignation: NKX2-5

Sujet:

Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

Gene Full Name: NK2 homeobox 5

ID gène: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development