NHEJ1 anticorps (AA 1-273) (Cy3)

N° du produit ABIN8016090

L’anticorps anti-NHEJ1 Polyclonal Lapin est utilisé pour la détection de NHEJ1 dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour NHEJ1 anticorps (AA 1-273) (Cy3) (ABIN8016090)

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NHEJ1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-NHEJ1 anticorps (Cy3)

Épitope: AA 1-273

Fonction: Anti-XLF/NHEJ1 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human XLF/NHEJ1 recombinant protein (Position: M1-E273).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NHEJ1

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Autre désignation: NHEJ1

Sujet:

Background: Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene. It is mapped to 2q35. Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

Gene Full Name: non-homologous end joining factor 1

ID gène: 79840

UniProt: Q9H9Q4

Pathways: Réparation de l'ADN