NUP98 anticorps (AA 728-1787) (Fluoro488)

N° du produit ABIN8017434

L’anticorps anti-NUP98 Polyclonal Lapin est utilisé pour la détection de NUP98 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour FACS.

Aperçu rapide pour NUP98 anticorps (AA 728-1787) (Fluoro488) (ABIN8017434)

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP98 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-NUP98 anticorps (Fluoro488)

Épitope: AA 728-1787

Fonction: Anti-NUP98 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human NUP98 shares 89.1%,89% amino acid (aa) sequence identity with mouse,rat NUP98,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NUP98 recombinant protein (Position: H728-I1787). Human NUP98 shares 89.1% and 89% amino acid (aa) sequence identity with mouse and rat NUP98, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NUP98

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Autre désignation: NUP98

Sujet:

Background: Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene. This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. NUP98 is a peripheral nucleoporin located at both the cytoplasmic and nuclear sides of the central channel of the NPC. NUP98 phosphorylation is critical for NPC disassembly at the onset of mitosis. It also plays roles in gene expression, mitotic checkpoint, and pathogenesis. Ligand blot analysis suggested that NUP98 can function as a docking protein for cytosol-mediated docking of import substrates. In addition to that, NUP98 is a target of the vesicular stomatitis virus M protein-mediated inhibition of mRNA nuclear export.

Gene Full Name: nucleoporin 98 and 96 precursor

ID gène: 4928

UniProt: P52948

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome