PAK4 anticorps (C-Term) (HRP)

N° du produit ABIN8019003

L’anticorps anti-PAK4 Polyclonal Lapin est utilisé pour la détection de PAK4 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PAK4 anticorps (C-Term) (HRP) (ABIN8019003)

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PAK4 anticorps (HRP)

Épitope: C-Term

Fonction: Anti-PAK4 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human PAK4.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PAK4

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Autre désignation: PAK4

Sujet:

Background: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Full Name: p21 (RAC1) activated kinase 4

ID gène: 10298

UniProt: O96013

Pathways: Signalisation RTK