PEX5 anticorps (Middle Region) (Cy3)

N° du produit ABIN8020774

Cet anticorps anti-PEX5 Polyclonal Lapin conjugué à Cy3 (ABIN8020774) détecte spécifiquement PEX5 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PEX5 anticorps (Middle Region) (Cy3) (ABIN8020774)

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEX5 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-PEX5 anticorps (Cy3)

Épitope: Middle Region

Fonction: Anti-PEX5 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse,rat PEX5.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PEX5. Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse and rat PEX5.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PEX5

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Autre désignation: PEX5

Sujet:

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: peroxisomal biogenesis factor 5

ID gène: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process