PEX5 anticorps (Middle Region) (PE)

N° du produit ABIN8020781

Cet anticorps Lapin Polyclonal détecte spécifiquement PEX5 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PEX5 anticorps (Middle Region) (PE) (ABIN8020781)

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEX5 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-PEX5 anticorps (PE)

Épitope: Middle Region

Fonction: Anti-PEX5 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse,rat PEX5.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PEX5. Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse and rat PEX5.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PEX5

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Autre désignation: PEX5

Sujet:

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: peroxisomal biogenesis factor 5

ID gène: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process