PIK3R5 anticorps (AA 170-864) (APC)

N° du produit ABIN8021919

L’anticorps anti-PIK3R5 Polyclonal Lapin est utilisé pour la détection de PIK3R5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PIK3R5 anticorps (AA 170-864) (APC) (ABIN8021919)

Antigène: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R5 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-PIK3R5 anticorps (APC)

Épitope: AA 170-864

Fonction: Anti-PIK3R5 Antibody APC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PIK3R5 recombinant protein (Position: E170-L864). Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PIK3R5

Antigène: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Autre désignation: PIK3R5

Sujet:

Background: Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

Gene Full Name: phosphoinositide-3-kinase regulatory subunit 5

ID gène: 23533

UniProt: Q8WYR1

Pathways: Signalisation PI3K-Akt, Inositol Metabolic Process, Hepatitis C, VEGF Signaling