Retinoblastoma 1 anticorps (AA 40-921) (Biotin)
Aperçu rapide pour Retinoblastoma 1 anticorps (AA 40-921) (Biotin) (ABIN8031763)
Antigène
Voir toutes Retinoblastoma 1 (RB1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-921
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Fonction
- Anti-RB1 Antibody Biotin Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human RB1 shares 91.6%,90.7% amino acid (aa) sequence identity with mouse,rat RB1,respectively.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human RB1 recombinant protein (Position: E40-D921). Human RB1 shares 91.6% and 90.7% amino acid (aa) sequence identity with mouse and rat RB1, respectively.
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Isotype
- IgG
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anti-Retinoblastoma 1 (RB1) (pSer612) antibody
RB1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB7659 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 586-615) antibodyRB1 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB7977 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 858-886), (C-Term) antibodyRB1 Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal RB20715 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 745-928) antibodyRB1 Reactivité: Humain WB, ELISA, ICC, FACS Hôte: Souris Monoclonal 2A11D11 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reactivité: Humain WB, IF, IP, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer788) antibodyRB1 Reactivité: Humain IHC (p), DB Hôte: Lapin Polyclonal RB7670 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer811) antibodyRB1 Reactivité: Humain IF, IHC (p), DB Hôte: Lapin Polyclonal RB7679 unconjugated
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Retinoblastoma 1 (RB1)
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Autre désignation
- RB1
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Sujet
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Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Gene Full Name: RB transcriptional corepressor 1
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ID gène
- 5925
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UniProt
- P06400
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Pathways
- Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
Antigène
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