RNF8 anticorps (AA 3-488) (Fluoro647)

N° du produit ABIN8033370

L’anticorps anti-RNF8 Polyclonal Lapin est utilisé pour la détection de RNF8 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour RNF8 anticorps (AA 3-488) (Fluoro647) (ABIN8033370)

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF8 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-RNF8 anticorps (Fluoro647)

Épitope: AA 3-488

Fonction: Anti-RNF8 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse RNF8 recombinant protein (Position: E3-S488).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RNF8

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Autre désignation: Rnf8

Sujet:

Background: E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.

Gene Full Name: ring finger protein 8

ID gène: 58230

UniProt: Q8VC56

Pathways: Production of Molecular Mediator of Immune Response