RYK anticorps (AA 66-607) (APC)

N° du produit ABIN8034202

Cet anticorps anti-RYK Polyclonal Lapin conjugué à APC (ABIN8034202) détecte spécifiquement RYK dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RYK anticorps (AA 66-607) (APC) (ABIN8034202)

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RYK est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-RYK anticorps (APC)

Épitope: AA 66-607

Fonction: Anti-RYK Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RYK

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Autre désignation: RYK

Sujet:

Background: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: receptor like tyrosine kinase

ID gène: 6259

UniProt: P34925

Pathways: Signalisation RTK, Signalisation WNT, Regulation of Cell Size