Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 594-1909) anticorps

N° du produit ABIN8041407

L’anticorps anti-Spectrin, Beta, Non-erythrocytic 2 Polyclonal Lapin est utilisé pour la détection de Spectrin, Beta, Non-erythrocytic 2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, FACS et ELISA.

Aperçu rapide pour Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 594-1909) anticorps (ABIN8041407)

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Classe de qualité: Carrier-free

Détail du produit

Épitope: AA 594-1909

Fonction: Anti-SPTBN2 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SPTBN2 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPTBN2 recombinant protein (Position: A594-K1909).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Autre désignation: SPTBN2

Sujet:

Background: Spectrin beta chain, brain 2 is a protein that in humans is encoded by the SPTBN2 gene. Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.

Gene Full Name: spectrin beta, non-erythrocytic 2

Poids moléculaire: 271 kDa

ID gène: 6712

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis