Stanniocalcin 2 anticorps (AA 51-226)
Aperçu rapide pour Stanniocalcin 2 anticorps (AA 51-226) (ABIN8042528)
Antigène
Voir toutes Stanniocalcin 2 (STC2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 51-226
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Fonction
- Anti-Stanniocalcin 2/STC2 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human STC2 shares 90.3%,89.8% amino acid (aa) sequence identity with mouse,rat STC2,respectively.
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Attributs du produit
- Anti-Stanniocalcin 2/STC2 Antibody. Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Stanniocalcin 2/STC2 recombinant protein (Position: A51-Q226). Human STC2 shares 90.3% and 89.8% amino acid (aa) sequence identity with mouse and rat STC2, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- Stanniocalcin 2 (STC2)
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Autre désignation
- STC2
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Sujet
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Background: Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Gene Full Name: stanniocalcin 2
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Poids moléculaire
- 33 kDa
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ID gène
- 8614
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UniProt
- O76061
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Pathways
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
Antigène
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