SRA1 anticorps (AA 1-224) (HRP)

N° du produit ABIN8042769

L’anticorps anti-SRA1 Polyclonal Lapin est utilisé pour la détection de SRA1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour SRA1 anticorps (AA 1-224) (HRP) (ABIN8042769)

Antigène: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRA1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SRA1 anticorps (HRP)

Épitope: AA 1-224

Fonction: Anti-SRA1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SRA1 shares 81.8%,80% amino acid (aa) sequence identity with mouse,rat SRA1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SRA1 recombinant protein (Position: M1-S224). Human SRA1 shares 81.8% and 80% amino acid (aa) sequence identity with mouse and rat SRA1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SRA1

Antigène: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Autre désignation: SRA1

Sujet:

Background: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Gene Full Name: steroid receptor RNA activator 1

ID gène: 10011

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development