SOCS2 anticorps (AA 96-198) (PE)

N° du produit ABIN8043742

Cet anticorps anti-SOCS2 Polyclonal Lapin conjugué à PE (ABIN8043742) détecte spécifiquement SOCS2 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour SOCS2 anticorps (AA 96-198) (PE) (ABIN8043742)

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-SOCS2 anticorps (PE)

Épitope: AA 96-198

Fonction: Anti-SOCS2 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human SOCS2 shares 96.1%,95.1% amino acid (aa) sequence identity with mouse,rat SOCS2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SOCS2

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Autre désignation: SOCS2

Sujet:

Background: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.

Gene Full Name: suppressor of cytokine signaling 2

Sequence Similarities: Contains 1 SH2 domain.

ID gène: 8835

UniProt: O14508

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus