TNIK anticorps (AA 1281-1360) (Cy3)

N° du produit ABIN754831

Cet anticorps Lapin Polyclonal détecte spécifiquement TNIK dans IF (p) et IF (cc). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour TNIK anticorps (AA 1281-1360) (Cy3) (ABIN754831)

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIK est conjugé à/à la Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-TNIK anticorps (Cy3)

Épitope: AA 1281-1360

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TNIK

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TNIK

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Autre désignation: TNIK

Sujet:

Synonyms: Traf2 and NCK interacting kinase, 1500031A17RIK, 4831440I19RIK, AI451411, C530008O15Rik, C630040K21RIK, KIAA0551, MGC189819, MGC189859, RGD1561817, TNIK, TNIK_HUMAN, TRAF2 and NCK-interacting protein kinase.

Background: TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.

ID gène: 23043