RRM2B anticorps (AA 131-230)

N° du produit ABIN755023

Cet anticorps Lapin Polyclonal détecte spécifiquement RRM2B dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour RRM2B anticorps (AA 131-230) (ABIN755023)

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RRM2B anticorps

Épitope: AA 131-230

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human p53R2/RRM2B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RRM2B

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Autre désignation: p53R2

Sujet:

Synonyms: DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, p53 inducible ribonucleotide reductase small subunit 2 homolog, p53 inducible ribonucleotide reductase small subunit 2 like protein, p53 R2, p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2, Ribonucleoside diphosphate reductase M2 subunit B, Ribonucleoside-diphosphate reductase subunit M2 B, Ribonucleotide reductase M2 B TP53 inducible, Ribonucleotide reductase M2 B, Ribonucleotide reductase small subunit like 2 p53 inducible, RIR2B_HUMAN, RRM 2B, RRM2B, TP53 inducible ribonucleotide reductase M2 B, TP53-inducible ribonucleotide reductase M2 B.

Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].

ID gène: 50484

Pathways: Signalisation p53, Negative Regulation of intrinsic apoptotic Signaling