TLR10 anticorps (N-Term) (APC)

N° du produit ABIN8047310

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR10 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TLR10 anticorps (N-Term) (APC) (ABIN8047310)

Antigène: TLR10 (Toll-Like Receptor 10 (TLR10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR10 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-TLR10 anticorps (APC)

Épitope: N-Term

Fonction: Anti-Toll-like receptor 10 TLR10 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human TLR10.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TLR10

Antigène: TLR10 (Toll-Like Receptor 10 (TLR10))

Autre désignation: TLR10

Sujet:

Background: TLR10 (Toll-like receptor 10), is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al. (2005) determined that the TLR10 gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al. (2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM (TICAM2), or TRIF (TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.

Gene Full Name: toll like receptor 10

Sequence Similarities: Belongs to the Toll-like receptor family.

ID gène: 81793

UniProt: Q9BXR5

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades