TIGAR anticorps (AA 1-270)

N° du produit ABIN8047632

L’anticorps anti-TIGAR Polyclonal Lapin est utilisé pour la détection de TIGAR dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC, IF, FACS et ICC.

Aperçu rapide pour TIGAR anticorps (AA 1-270) (ABIN8047632)

Antigène: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIGAR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Détail du produit anti-TIGAR anticorps

Épitope: AA 1-270

Fonction: Anti-TIGAR Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human TIGAR shares 72.8% amino acid (aa) sequence identity with mouse TIGAR.

Attributs du produit: Anti-TIGAR Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TIGAR recombinant protein (Position: M1-R270). Human TIGAR shares 72.8% amino acid (aa) sequence identity with mouse TIGAR.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TIGAR

Antigène: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Autre désignation: TIGAR

Sujet:

Background: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

Gene Full Name: TP53 induced glycolysis regulatory phosphatase

Poids moléculaire: 30 kDa

ID gène: 57103

UniProt: Q9NQ88

Pathways: L'effet Warburg