Bax Inhibitor 1 anticorps (N-Term) (PE)

N° du produit ABIN8048874

L’anticorps anti-Bax Inhibitor 1 Polyclonal Lapin est utilisé pour la détection de Bax Inhibitor 1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour Bax Inhibitor 1 anticorps (N-Term) (PE) (ABIN8048874)

Antigène: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bax Inhibitor 1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Bax Inhibitor 1 anticorps (PE)

Épitope: N-Term

Fonction: Anti-BI-1/TMBIM6 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human BI-1/TMBIM6, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Bax Inhibitor 1

Antigène: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Autre désignation: TMBIM6

Sujet:

Background: Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.

Gene Full Name: transmembrane BAX inhibitor motif containing 6

ID gène: 7009

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling