TPP1 anticorps (Middle Region) (FITC)

N° du produit ABIN8050028

Cet anticorps Lapin Polyclonal détecte spécifiquement TPP1 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TPP1 anticorps (Middle Region) (FITC) (ABIN8050028)

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPP1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-TPP1 anticorps (FITC)

Épitope: Middle Region

Fonction: Anti-TPP1 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by six amino acids,and from the related rat sequence by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TPP1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TPP1

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Autre désignation: TPP1

Sujet:

Background: Tripeptidyl-peptidase 1, also known as Lysosomal pepstatin-insensitive protease, is an enzyme that in humans is encoded by the TPP1 gene. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Gene Full Name: tripeptidyl peptidase 1

ID gène: 1200

UniProt: O14773

Pathways: Cycle Cellulaire, ER-Nucleus Signaling