TDP1 anticorps (AA 1-499) (Fluoro550)

N° du produit ABIN8051867

Cet anticorps Lapin Polyclonal détecte spécifiquement TDP1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TDP1 anticorps (AA 1-499) (Fluoro550) (ABIN8051867)

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDP1 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-TDP1 anticorps (Fluoro550)

Épitope: AA 1-499

Fonction: Anti-TDP1 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human TDP1 shares 78.8%,79.6% amino acid (aa) sequence identity with mouse,rat TDP1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TDP1 recombinant protein (Position: M1-R499). Human TDP1 shares 78.8% and 79.6% amino acid (aa) sequence identity with mouse and rat TDP1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TDP1

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Autre désignation: TDP1

Sujet:

Background: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).

Gene Full Name: tyrosyl-DNA phosphodiesterase 1

ID gène: 55775

UniProt: Q9NUW8