UCHL1 anticorps (C-Term) (Biotin)

N° du produit ABIN8051974

Cet anticorps anti-UCHL1 Monoclonal Souris conjugué à Biotin (Clone 3E4) (ABIN8051974) détecte spécifiquement UCHL1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour UCHL1 anticorps (C-Term) (Biotin) (ABIN8051974)

Antigène: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UCHL1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3E4

Détail du produit anti-UCHL1 anticorps (Biotin)

Épitope: C-Term

Fonction: Anti-PGP9.5 Antibody (monoclonal, 3E4) Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse,rat sequences by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human PGP9.5, different from the related mouse and rat sequences by two amino acids.

Isotype: IgG1

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur UCHL1

Antigène: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Autre désignation: UCHL1

Sujet:

Background: UCH-L1, also known as PGP9.5, is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is abundantly present in all neurons (accounts for 1-2 % of total brain protein), expressed specifically in neurons and testis/ovary. The catalytic triad of UCH-L1 contains a cysteine at position 90, an aspartate at position 176, and a histidine at position 161 that are responsible for its hydrolase activity.

Gene Full Name: ubiquitin C-terminal hydrolase L1

ID gène: 7345

UniProt: P09936

Pathways: Feeding Behaviour