UBD anticorps (N-Term) (APC)

N° du produit ABIN8052037

Cet anticorps anti-UBD Polyclonal Lapin conjugué à APC (ABIN8052037) détecte spécifiquement UBD dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour UBD anticorps (N-Term) (APC) (ABIN8052037)

Antigène: UBD (Ubiquitin D (UBD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBD est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-UBD anticorps (APC)

Épitope: N-Term

Fonction: Anti-Diubiquitin/UBD Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Diubiquitin, different from the related mouse and rat sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur UBD

Antigène: UBD (Ubiquitin D (UBD))

Autre désignation: UBD

Sujet:

Background: Ubiquitin D, also called UBD or FAT10 is a protein that in humans is encoded by the UBD gene. This gene is mapped to 6p22.1. Ubiquitin-like protein modifier can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. This gene mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It probably functions as a survival factor.

Gene Full Name: ubiquitin like modifier D

Sequence Similarities: Contains 2 ubiquitin-like domains.

ID gène: 10537

UniProt: O15205

Pathways: Ubiquitin Proteasome Pathway