WHSC2 anticorps (AA 38-482) (Cy3)

N° du produit ABIN8054481

L’anticorps anti-WHSC2 Polyclonal Lapin est utilisé pour la détection de WHSC2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour WHSC2 anticorps (AA 38-482) (Cy3) (ABIN8054481)

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WHSC2 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-WHSC2 anticorps (Cy3)

Épitope: AA 38-482

Fonction: Anti-NELFA Antibody Cy3 Conjugated

Homologie: Human NELFA shares 94.6% amino acid (aa) sequence identity with mouse NELFA.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NELFA recombinant protein (Position: I38-L482). Human NELFA shares 94.6% amino acid (aa) sequence identity with mouse NELFA.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur WHSC2

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Autre désignation: NELFA

Sujet:

Background: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Gene Full Name: negative elongation factor complex member A

ID gène: 7469

UniProt: Q9H3P2

Pathways: Chromatin Binding