WFS1 anticorps (AA 61-313) (Cy3)

N° du produit ABIN8054492

Cet anticorps Lapin Polyclonal détecte spécifiquement WFS1 dans FACS. Il présente une réactivité avec des échantillons de Humain et Singe.

Aperçu rapide pour WFS1 anticorps (AA 61-313) (Cy3) (ABIN8054492)

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WFS1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-WFS1 anticorps (Cy3)

Épitope: AA 61-313

Fonction: Anti-WFS1 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human WFS1 recombinant protein (Position: A61-H313).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur WFS1

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Autre désignation: WFS1

Sujet:

Background: Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: wolframin ER transmembrane glycoprotein

ID gène: 7466

UniProt: O76024

Pathways: Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome