DNMT1 anticorps (pSer154)

N° du produit ABIN757717

Détail du produit anti-DNMT1 anticorps

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Épitope: pSer154

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT1 est non-conjugé

Application: ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Dnmt1 around the phosphorylation site of Ser153

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-DNMT1 (ABIN757717)

Tan, Xu, Zeisberg, Zeisberg: "High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation." dans: Biochemical and biophysical research communications, Vol. 472, Issue 3, pp. 459-64, (2016) (PubMed).

Détails sur DNMT1

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Autre désignation: Dnmt1 (DNMT1 Produits)

Sujet:

Synonyms: Dnmt1phospho S154, Dnmt1 phospho Ser154, p-Dnmt1 Ser154, AIM, CXXC finger protein 9, CXXC-type zinc finger protein 9, CXXC9, DNA cytosine 5 methyltransferase 1, DNA cytosine-5-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA methyltransferase M.HsaI., DNA MTase, DNA MTase HsaI, DNMT 1, DNMT, Dnmt1, Dnmt1, DNMT1_HUMAN, Dnmt1o, FLJ16293, HSN1E, M.HsaI, MCMT, Met1, MGC104992, mMmul, MommeD2.

Background: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

ID gène: 1786

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2