desert Hedgehog anticorps (AA 101-200)

N° du produit ABIN759686

L’anticorps Lapin Polyclonal anti-desert Hedgehog a été validé pour WB, ELISA, IF (cc), IF (p), IHC (fro) et IHC (p). Il convient pour détecter desert Hedgehog dans des échantillons de Souris.

Aperçu rapide pour desert Hedgehog anticorps (AA 101-200) (ABIN759686)

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp desert Hedgehog est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-desert Hedgehog anticorps

Épitope: AA 101-200

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DHH

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur desert Hedgehog

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Autre désignation: DHH

Classe de substances: Species

Sujet:

Synonyms: Desert hedgehog Drosophila homolog, Desert hedgehog, Desert hedgehog homolog Drosophila, Desert hedgehog protein precursor.

Background: This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N terminal portion is soluble and contains the signalling activity while the C terminal portion is involved in precursor processing. More importantly, the C terminal product covalently attaches a cholesterol moiety to the N terminal product, restricting the N terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

ID gène: 50846

Pathways: Signalisation Hedgehog