MAS1 anticorps (AA 51-150)

N° du produit ABIN759911

L’anticorps Lapin Polyclonal anti-MAS1 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter MAS1 dans des échantillons de Humain et Souris.

Aperçu rapide pour MAS1 anticorps (AA 51-150) (ABIN759911)

Antigène: MAS1 (MAS1 Oncogene (MAS1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MAS1 anticorps

Épitope: AA 51-150

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAS1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MAS1

Antigène: MAS1 (MAS1 Oncogene (MAS1))

Autre désignation: MAS1

Sujet:

Synonyms: MAS, MGRA, Proto-oncogene Mas, MAS1

Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

ID gène: 4142

UniProt: P04201

Pathways: ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process