MAS1 anticorps (Cy5)
Aperçu rapide pour MAS1 anticorps (Cy5) (ABIN759915)
Antigène
Voir toutes MAS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris
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Homologie
- Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human MAS1
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Isotype
- IgG
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Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- MAS1 (MAS1 Oncogene (MAS1))
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Autre désignation
- Mas1
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Sujet
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Synonyms: MAS, MGRA, Proto-oncogene Mas, MAS1
Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
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ID gène
- 4142
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UniProt
- P04201
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Pathways
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
Antigène
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