TICAM2 anticorps (N-Term)

N° du produit ABIN8113977

Cet anticorps anti-TICAM2 Polyclonal Lapin (ABIN8113977) détecte spécifiquement TICAM2 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TICAM2 anticorps (N-Term) (ABIN8113977)

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TICAM2 anticorps

Épitope: N-Term

Fonction: TICAM2 Antibody - N-terminal region

Séquence: VDTSPGYHES DSKKSEDLSL CNVAEHSNTT EGPTGKQEGA QSVEEMFEEE

Homologie: Human: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCAM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64855-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TICAM2

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: TICAM2

Sujet:

Background Information: This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway.

Gene Name: TMED7-TICAM2 readthrough

Alternative Symbols: TIRP, TRAM, TICAM2, TIRAP3, MyD88-4, TICAM-2

Protein Name: TRAM adaptor with GOLD domain

Poids moléculaire: 25kDa

ID gène: 100302736

NCBI Accession: NP_067681

UniProt: Q86XR7

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades