ACLY anticorps

N° du produit ABIN8119859

Cet anticorps Lapin Monoclonal détecte spécifiquement ACLY dans WB, ELISA, IHC, IF et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ACLY anticorps (ABIN8119859)

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ACLY est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2029

Détail du produit anti-ACLY anticorps

Fonction: ATP-Citrate Lyase Rabbit mAb

Specificité: This antibody detects endogenous levels of ATP-Citrate Lyase protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur ACLY

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: ATP-Citrate Lyase

Sujet:

Synonyms: ACLY, ATP-citrate synthase, ATP-citrate, pro-S-)-lyase, ACL, Citrate cleavage enzyme

Background: ATP citrate lyase (ACLY) Homo sapiens    ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

Gene Name: ACLY

Protein Name: ATP-Citrate Lyase

ID gène: 47

UniProt: P53396

Pathways: L'effet Warburg