AXL anticorps
Aperçu rapide pour AXL anticorps (ABIN8119931)
Antigène
Voir toutes AXL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Axl Rabbit mAb
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Specificité
- This antibody detects endogenous levels of Axl protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- AXL (AXL Receptor tyrosine Kinase (AXL))
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Autre désignation
- Axl
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Sujet
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Synonyms: AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene
Background: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) . This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Gene Name: AXL UFO
Protein Name: Axl
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ID gène
- 558
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UniProt
- P30530
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Pathways
- Signalisation RTK, Cellular Response to Molecule of Bacterial Origin
Antigène
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