Survivin anticorps

N° du produit ABIN8119953

L’anticorps anti-Survivin Monoclonal Lapin est utilisé pour la détection de Survivin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IP.

Aperçu rapide pour Survivin anticorps (ABIN8119953)

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB1829

Détail du produit anti-Survivin anticorps

Fonction: Survivin Rabbit mAb

Specificité: This antibody detects endogenous levels of Survivin protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: Survivin

Sujet:

Synonyms: BIRC5, API4, IAP4, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin

Background: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],

Gene Name: >>Platinum drug resistance, >>Apoptosis, >>Apoptosis-multiple species, >>Hippo signaling pathway, >>Hepatitis B, >>Pathways in cancer, >>Chemical carcinogenesis-receptor activation, >>Colorectal cancer

Protein Name: Survivin

ID gène: 332

UniProt: O15392

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding