Cadherin-16 anticorps (AA 700-829)

N° du produit ABIN8120100

L’anticorps anti-Cadherin-16 Monoclonal Souris est utilisé pour la détection de Cadherin-16 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Cadherin-16 anticorps (AA 700-829) (ABIN8120100)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1739

Détail du produit anti-Cadherin-16 anticorps

Épitope: AA 700-829

Fonction: KSP-Cadherin mouse mAb

Specificité: The antibody can specifically recognize human KSP-Cadherin protein, and has no cross reaction with E-cadherin, N-cadherin, P-cadherin.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 700 - 829 of the human KSP - Cadherin protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: KSP-Cadherin

Sujet:

Synonyms: CAD16_HUMAN, Cadherin 16, Cadherin 16 KSP cadherin, Cadherin kidney, Cadherin-16, CDH 16, CDH16, Kidney cadherin, Kidney specific cadherin, Kidney-specific cadherin, Ksp cadherin, Ksp-cadherin, PRO1340, UNQ695

Background: KSP-cadherin, also known as cadherin-16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP-cadherin has a sensitivity of up to 100 % in renal chromophobe cell carcinoma and 95 % in renal eosinophilic adenoma.

Gene Name: CDH16

Protein Name: KSP-Cadherin

ID gène: 1014

UniProt: O75309