CAMLG anticorps

N° du produit ABIN8120132

Cet anticorps Lapin Polyclonal détecte spécifiquement CAMLG dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CAMLG anticorps (ABIN8120132)

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMLG est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CAMLG anticorps

Fonction: CAMLG Antibody

Specificité: CAMLG Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CAMLG

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Autre désignation: CAMLG

Sujet:

Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin.The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],

Gene Name: CAMLG CAML

Protein Name: Calcium signal-modulating cyclophilin ligand (CAML)

ID gène: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway