Caspase 10 anticorps (Cleaved-Ala416)

N° du produit ABIN8120226

L’anticorps anti-Caspase 10 Polyclonal Lapin est utilisé pour la détection de Caspase 10 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Caspase 10 anticorps (Cleaved-Ala416) (ABIN8120226)

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 10 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Caspase 10 anticorps

Épitope: Cleaved-Ala416

Fonction: Caspase 10 (p12, Cleaved-Ala416) Antibody

Specificité: This antibody detects endogenous levels of Human Caspase 10 (p12, Cleaved-Ala416, protein was cleaved amino acid sequence between 415-416)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human Caspase 10 (p12, Cleaved-Ala416)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Caspase 10

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Autre désignation: Caspase 10

Sujet:

Synonyms: Caspase-10 (CASP-10, EC 3.4.22.63, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17, Caspase-10 subunit p12]

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

Gene Name: CASP10 MCH4

Protein Name: Caspase10

ID gène: 843

UniProt: Q92851

Pathways: Apoptose, Caspase Cascade in Apoptosis