CASP14 anticorps (AA 110-190)

N° du produit ABIN8120229

L’anticorps anti-CASP14 Polyclonal Lapin est utilisé pour la détection de CASP14 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour CASP14 anticorps (AA 110-190) (ABIN8120229)

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP14 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CASP14 anticorps

Épitope: AA 110-190

Fonction: Caspase-14 Antibody

Specificité: Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Caspase-14 . at AA range: 110-190

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CASP14

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Autre désignation: Caspase-14

Sujet:

Synonyms: CASP14, Caspase-14, CASP-14

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008],

Gene Name: CASP14

Protein Name: Caspase14

ID gène: 23581

UniProt: P31944