CFHR5 anticorps (AA 353-403)

N° du produit ABIN8120724

L’anticorps anti-CFHR5 Polyclonal Lapin est utilisé pour la détection de CFHR5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour CFHR5 anticorps (AA 353-403) (ABIN8120724)

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CFHR5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CFHR5 anticorps

Épitope: AA 353-403

Fonction: FHR5 Antibody

Specificité: This antibody detects endogenous levels of FHR5 at Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human FHR5 AA range: 353-403

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CFHR5

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Autre désignation: FHR5

Sujet:

Synonyms: Complement factor H-related protein 5 (FHR-5)

Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation.The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],

Gene Name: CFHR5 CFHL5 FHR5

Protein Name: FHR5

ID gène: 81494

UniProt: Q9BXR6