CDKN1C anticorps (AA 200-316)

N° du produit ABIN8120824

Cet anticorps anti-CDKN1C Monoclonal Lapin (Clone AB1822) (ABIN8120824) détecte spécifiquement CDKN1C dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDKN1C anticorps (AA 200-316) (ABIN8120824)

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDKN1C est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1822

Détail du produit anti-CDKN1C anticorps

Épitope: AA 200-316

Fonction: p57kip2 Rabbit mAb (Ready to Use)

Specificité: The antibody can specifically recognize human p57kip2 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur CDKN1C

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Autre désignation: p57kip2

Sujet:

Synonyms: Beckwith Wiedemann syndrome,BWCR,BWS,CDKI,CDKN 1C,CDKN1C,CDN1C_HUMAN,Cyclin dependent kinase inhibitor 1C,Cyclin dependent kinase inhibitor p57,Cyclin-dependent kinase inhibitor 1C,Cyclin-dependent kinase inhibitor p57,KIP 2,KIP2,p57,p57 Kip 2,p57KIP2,WBS

Background: P57kip2 is a cell cycle inhibitor and tumor suppressor. The gene is mainly located on the mother's chromosome 11. By blocking the G1 / S phase transition in the cell cycle, we can realize the negative regulation of the cell cycle, and then prevent cell proliferation and tumor formation. In complete hydatidiform mole, there is a lack of maternal gene and p57 negative expression, while in partial hydatidiform mole, there are genes of both parents and p57 positive expression, which can be used for the study of early hydatidiform mole pregnancy.

Gene Name: CDKN1C

Protein Name: p57kip2

ID gène: 1028

UniProt: P49918

Pathways: Cycle Cellulaire, Dopaminergic Neurogenesis