CYFIP2 anticorps (AA 1171-1220)

N° du produit ABIN8120893

Cet anticorps anti-CYFIP2 Polyclonal Lapin (ABIN8120893) détecte spécifiquement CYFIP2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CYFIP2 anticorps (AA 1171-1220) (ABIN8120893)

Antigène: CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYFIP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CYFIP2 anticorps

Épitope: AA 1171-1220

Fonction: CYFIP2 Antibody

Specificité: CYFIP2 Polyclonal Antibody detects endogenous levels of CYFIP2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from CYFIP2 at AA range: 1171-1220

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CYFIP2

Antigène: CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2))

Autre désignation: CYFIP2

Sujet:

Synonyms: Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)

Background: disease:Up-regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis (at protein level).,function:Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA.,induction:By p53.,RNA editing:Partially edited. Editing appears to be brain-specific.,similarity:Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus.,subunit:Interacts with FMR1, FXR1 AND FXR2. Component of the WAVE1 complex composed of ABI2, CYFIP2, C3orf10/HSPC300, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1.,

Gene Name: CYFIP2

Protein Name: CYFIP2

ID gène: 26999

UniProt: Q96F07

Pathways: Signalisation RTK, Apoptose, Positive Regulation of Endopeptidase Activity