p300 anticorps (AA 1-100)

N° du produit ABIN8121098

Cet anticorps Souris Monoclonal détecte spécifiquement p300 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour p300 anticorps (AA 1-100) (ABIN8121098)

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p300 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2463

Détail du produit anti-p300 anticorps

Épitope: AA 1-100

Fonction: p300 mouse mAb

Specificité: This antibody detects endogenous levels of p300 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human p300 protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur p300

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Autre désignation: p300

Sujet:

Synonyms: EP300, P300, Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300

Background: E1A binding protein p300 (EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha) , and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],

Gene Name: EP300

Protein Name: p300

ID gène: 2033

UniProt: Q09472

Pathways: Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size