FGD1 anticorps (AA 508-558)

N° du produit ABIN8121548

Cet anticorps Lapin Polyclonal détecte spécifiquement FGD1 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour FGD1 anticorps (AA 508-558) (ABIN8121548)

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FGD1 anticorps

Épitope: AA 508-558

Fonction: FGD1 Antibody

Specificité: This antibody detects endogenous levels of FGD1 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human FGD1 AA range: 508-558

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FGD1

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Autre désignation: FGD1

Sujet:

Synonyms: FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)

Background: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],

Gene Name: FGD1 FGDY ZFYVE3

Protein Name: FGD1

ID gène: 2245

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway